Metabolomics News Monitoring

From Bench to Bedside: Multifunctional Nanoplatforms in the Fight Against Non-alcoholic Fatty Liver Disease

Introduction Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent liver disease globally, affecting approximately 25% of the adult population.1 With the global obesity epidemic, the incidence of NAFLD has exhibited a significant upward …

A spatiotemporal transcriptomic atlas of the mouse placenta reveals glycogen cell-mediated metabolic support essential ...

The placenta, a sophisticated and unique organ, plays an indispensable role during mammalian pregnancy. It not only serves as a physical barrier between maternal blood and the fetus, but also performs crucial functions such as delivering oxygen and …

Metabolic Multimorbidity and Risk of All-Cause and Cause-Specific Mortality: A Retrospective Cohort Study of 123,791 ...

Xianhui Ran,1,* Zhiyuan Fan,1,* Na Wang,1,* Tianyi Zhao,1 Hui Li,1 Xiao Liu,2 Enying Gong,3 Shuanghua Xie,4 Beiyao Gao,5 Lan An,6 Gang Chen,1 Xiao Ma,1,7 Chen Wang3,7 1Health Checkup Center, China-Japan Friendship Hospital, Beijing …

Dissecting the Causal Pathway from Herpes Zoster to Postherpetic Neuralgia: A Multi-Stage Mendelian Randomization Study ...

Introduction Postherpetic neuralgia (PHN) represents the most debilitating complication of herpes zoster (HZ), affecting 10–20% of patients and imposing substantial burdens on quality of life and healthcare resources.1–3 Despite the availability of …

Impact of Neutrophils on the Tissue Microenvironment During Intestinal Inflammation

Introduction Neutrophils (polymorphonuclear leukocytes, PMN) are the most abundant circulating leukocytes and among the first responders to sites of mucosal injury and infection. Traditionally viewed as short-lived effector cells specialized in microbial …

Network Pharmacology-Serum Metabolomics Integration Identifies Key Targets, Biomarkers and Mechanism of Sendeng-4 in ...

Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized primarily by inflammatory synovitis. According to the Global Burden of Disease (GBD) study1, in 2020, the global prevalence of RA was approximately 17.6 million, …

Metabolomics across scales: from single cells to population studies

Johnson, C. H., Ivanisevic, J. & Siuzdak, G. Metabolomics: beyond biomarkers and towards mechanisms. Nat. Rev. Mol. Cell Biol. 17, 451–459 (2016). Article  CAS  PubMed  PubMed Central  Google Scholar  Wellen, K. E. & Thompson, C. B. A two-way …

Before AI Meets Your Biobank: Five Must-Do Steps for Research Institutions

This is the first in a series of blog posts focused on AI and clinical trials/research space, highlighting topics to be discussed at the upcoming BIO International convention on June 22-25, 2026. A major research institution combines 15 years of …

Insulin Resistance Across Cerebrovascular and Related Disorders: Mechanisms, Measurement, Genetics, and Clinical ...

1Department of Neurology, Guangxi Medical University Kaiyuan Langdong Hospital, Nanning, 530023, People’s Republic of China; 2Department of Rehabilitation Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530005, People’s …

Network Pharmacology, Molecular Docking and Dynamics Simulation Reveal the Anti-Colitis Mechanism of Smilax glabra Roxb.

1Department of Gastroenterology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210001, People’s Republic of China; 2Department of Gastroenterology, Ningxian Second People’s Hospital, …

Development and Validation of Predictive Machine Learning Models for Postoperative Recurrence and Microvascular Invasion ...

Introduction Liver cancer remains a major global health burden, with the Global Cancer Observatory reporting 865,000 new cases and 757,948 deaths worldwide in 2022.1 Hepatocellular carcinoma (HCC) is the main form of liver cancer, accounting for …

Sapient Launches Tumor Protein Mapping Platform to Characterize Functional Biology Across Critical Dimensions in Human ...

SAN DIEGO--(BUSINESS WIRE)--Apr 28, 2026-- Sapient, a leader in multi-omics data generation for biomarker discovery and clinical insight delivery, has announced the launch of its Tumor Protein Mapping Platform as a suite of mass spectrometry-based …

Targeted metabolomics reveals the optimal harvest time of Cabernet Sauvignon grapes in an emerging high‐altitude ...

Linoleic Acid Reduces Paclitaxel Chemosensitivity in Colorectal Cancer

Introduction Paclitaxel, a natural anticancer agent derived from Taxus chinensis, has demonstrated significant therapeutic efficacy in various solid tumors, including gastric, liver, lung, and breast cancers.1–4 Its primary mechanism involves binding to …

Decoding the Language of Plants and Microbes Using AI

Biologists and engineers have been working together over decades to decipher the language of biology. Now, they are teaching AI models to interpret that knowledge and harness it for national priorities through the Orchestrated Platform for Autonomous …

Rethinking Supplements Through a Pharmaceutical Lens

Traditionally focused on innovative prescription drugs and complex therapies, the pharmaceutical industry is now being reshaped by evolving consumer expectations, rapid scientific advancements, and a global shift toward preventive healthcare. As …

rs10010131A in WFS1 is Associated with Elevated Serum Urea in Type 2 Diabetes Patients Treated with SGLT2 Inhibitors

Introduction Type 2 diabetes (T2D) is a heterogeneous metabolic disorder with marked variation in clinical presentation, disease progression, and treatment response.1 While metformin remains the first-line therapy, newer agents such as sodium–glucose …

AI-Driven Phenotype-Target Coupled Screening Unveils Novel Approaches in Herbal Drug Discovery

In the emerging landscape of drug discovery, Chinese herbal medicines (CHMs) have long represented both a rich resource and a complex challenge. Despite their historical importance in traditional Chinese medicine (TCM) and their contribution to …

Natural compound obakulactone shows therapeutic potential for rheumatoid arthritis

A new study published in Engineering reveals that obakulactone (OL), a natural tetracyclic triterpenoid isolated from Phellodendri cortex, exerts a therapeutic effect on rheumatoid arthritis (RA) by promoting the degradation of acyl coenzyme A thioesterase …

As Milken Global Conference Opens, Saudi Arabia’s KFSH Brings an AI-as-Infrastructure Approach to Healthcare

RIYADH, SAUDI ARABIA, May 1, 2026 /⁨EINPresswire.com⁩/ -- As the Milken Institute Global Conference opens May 3 in Los Angeles, King Faisal Specialist Hospital and Research Centre (KFSH) enters the conversation with an approach that positions artificial …

Splinterlands Community to Support Initiative for Players Impacted by Game Shutdowns Across the Web3 Ecosystem

MEDIA, PA, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- SPS DAO Proposes Crypto Gaming Recovery Fund Sponsorship for Displaced Web3 Gamers Splinterlands Community to Support Initiative for Players Impacted by Game Shutdowns Across the Web3 Ecosystem …

Seedance 2.0 Premieres in Hollywood: Revolutionary AI Video Model Makes Grand Entrance to US Entertainment Industry

AI Filmmaking meets Hollywood as 600+ experience Seedance 2.0 firsthand, headlined by first-ever Golden Seed AI Film Awards SANTA MONICA, CA, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- The future of filmmaking arrived in the US and …

Global Memory Shortage Worsens with AI Demand as Vyrian Expands Supply of HBM, DRAM, NAND, and SSD Solutions

With ISO 17025 labs in Houston and Hong Kong, AS6171 inspection, and AI sourcing, Vyrian secures HBM, DRAM, NAND, and SSD supply with speed and confidence. HOUSTON, TX, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- Vyrian, a global semiconductor and …

ClaimCrush Launches AI That Fact-Checks Videos, Live Streams, and Debates in Real Time

New platform verifies claims across YouTube Live, Discord, and social media with structured verdicts and real sources. SAN FRANCISCO, CA, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- ClaimCrush, an AI-powered fact-checking platform, today …

ZeroMS Applies Real-Time Machine Learning to Order Execution, Redefining Broker Infrastructure

ZeroMS applies real-time machine learning to order execution, enabling brokers to detect behaviour and adapt routing decisions instantly. DUBAI, DUBAI, UNITED ARAB EMIRATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- ZeroMS, the multi-location FIX 4.4 …

PNXP Launches ExecutivesBOT The First Governed AI Executive Team Purpose-Built for Public Companies

Six AI executives, operate under board-supervised control with hash-chained audit trails, Reg FD compliance screening, and 50% discount through July 31, 2026. Pineapple Express Cannabis Company (OTCMKTS:PNXP) ATLANTA, GA, UNITED STATES, May 1, 2026 …

Reactive Media Statement

HOUSTON, TX, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- Morae is aware of an online claim alleging a potential security incident involving a legacy cloud environment that is not connected to our corporate environment. Upon becoming aware of …

Boys & Girls Clubs of Volusia/Flagler Showcases Future-Ready Innovation Through Boeing-Supported Launchpad Program

The BGCVFC Rossmeyer Campus in Holly Hill proudly hosted its Future U Launchpad on April 29th; made possible through the 2025 Boeing Future U Launchpad grant. HOLLY HILL, FL, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- The Boys & Girls …

Why AI-Enhanced Compliance Reporting Is Improving Healthcare Risk Management

NEW YORK CITY, PA, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- Healthcare adoption of artificial intelligence (AI) is growing, according to the American Hospital Association who reports 40% of U.S. community hospitals are leveraging AI or …

Abstract Rolls Out Native Linux Support: Built for the Pipelines that Power Production

While others pull back from Linux, Abstract goes native, bringing InstaMAT and InstaLOD to the OS that serious production pipelines are already built on. STUTTGART, GERMANY, May 1, 2026 /⁨EINPresswire.com⁩/ -- Abstract, a deep-tech company pioneering …

American Solution Store Expands Global Micro-Lending Efforts Through Kiva

Company supports entrepreneurs across six countries through micro-loans, helping generate reliable income and encouraging broader participation. UPSTATE, SC, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- American Solution Store, an …

Topcone Inc. Delivers Integrated Warehouse and Dispatch Management System for Warehousing Replacing Manual Operations

A warehousing & distribution firm eliminates paper-based dispatch operations after Topcone builds an integrated real-time warehouse & dispatch management system PORTER RANCH, CA, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- Topcone …

3PDelivery615 Offers Premium White Glove Delivery and Designer Receiving Services in Franklin, TN

Specialized logistics for high-value furniture, antiques, and designer pieces, now serving interior designers and luxury homes in Franklin, TN. FRANKLIN, TN, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- 3PDelivery615, a locally based …

A Saudi Hospital Cut the Cost of CAR-T by 80 Percent

RIYADH, SAUDI ARABIA, May 1, 2026 /⁨EINPresswire.com⁩/ -- As the Milken Institute Global Conference convenes in Los Angeles next week, one set of operational data from outside the United States is drawing attention in discussions on the future of …

Volta Electric Adds Smart Lighting and Home Automation Installations to Residential Services in California

New residential service helps California homeowners upgrade lighting control, comfort, safety, and energy efficiency with professional electrical installation. WEST HOLLYWOOD, CA, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- Volta Electric …

ABB Showcases Cutting-edge Converter Tech with GENBETA racecar at 2026 Hankook Berlin E-Prix

ABB to utilise the Formula E platform to showcase cutting-edge converter technology in the GENBETA Car at the 2026 Hankook Berlin E-Prix ZURICH, SWITZERLAND, May 1, 2026 /⁨EINPresswire.com⁩/ -- Utilising Formula E as a platform, ABB will unveil …

FLEET DATA CENTERS ANNOUNCES CLOSING OF UPSIZED $4.6B 6.500% SENIOR SECURED NOTES OFFERING TO FUND HYPERSCALE FACILITY

SENIOR SECURED NOTES OFFERING TO FUND HYPERSCALE FACILITY IN RAPIDLY GROWING RENO HUB DENVER, CO, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- Fleet Data Centers, a developer and operator of mega-scale, single-user data center campuses and …

BigHand’s Bríana McCrory Wins Outstanding Achievement Award

Industry recognition highlights her leadership as hundreds of legal leaders prepare for the upcoming BigHand Conference. LONDON, UNITED KINGDOM, May 1, 2026 /⁨EINPresswire.com⁩/ -- BigHand today announced that Bríana McCrory, Chief Marketing …

How Technology Is Transforming Remote Community Service Through The People Foundation’s Programs

Technology driven programs from The People Foundation expand access to flexible remote community service while building skills and increasing impact POST FALLS, ID, UNITED STATES, May 1, 2026 /⁨EINPresswire.com⁩/ -- Community service has long been …