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Published on 11:06 GMT

GLP-1R Agonists Rewire Energy to Combat Alzheimer’s

In a groundbreaking study poised to transform our understanding of neurodegenerative diseases, researchers have unveiled compelling evidence that GLP-1 receptor (GLP-1R) agonists hold significant promise in the fight against Alzheimer’s disease through a …

Source: Bioengineer.org - Pending
Published on May 30, 2025

Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells

Although the human body contains trillions of cells that could potentially be targeted by oncogenic mutations, cancers arise infrequently throughout a human lifetime, suggesting the presence of effective resistant mechanisms (Lowe et al., 2004). One key …

Source: eLife - Pending
Published on May 30, 2025

Sphingolipid imbalance aggravates tau pathology by endomembrane rigidification and rupture

The gradual accumulation of microtubule-associated protein tau (MAPT/tau) aggregates is a hallmark of Alzheimer’s disease (AD) and related tauopathies. Misfolded tau species exhibit prion-like behavior by self-replicating and spreading from cell to …

Source: eLife - Pending
Published on May 30, 2025

Deep Learning Reveals Endogenous Sterols as Allosteric Modulators of the GPCR-Gα Interface

G protein-coupled receptors (GPCRs) are critical regulators of cellular processes and thus represent prime drug targets (1–3). While traditional GPCR-targeted therapies focus on orthosteric sites, recent advances have revealed allosteric sites offering …

Source: eLife - Pending
Published on May 30, 2025

The integration mechanism of the four positional cues—anterior, posterior, dorsal, and ventral—in axolotl limb ...

Axolotls (Ambystoma mexicanum) possess remarkable regenerative abilities, enabling the regeneration of entire limbs after amputation. Among tetrapods (four-limbed vertebrates), only urodele amphibians retain the lifelong ability to regenerate fully …

Source: eLife - Pending
Published on May 30, 2025

Trump says he is doubling tariffs on imported steel to 50%

Trump says he is doubling tariffs on imported steel to 50%Donald Trump just announced at his rally in Pittsburgh that he is increasing the tariff on imported steel from 25% to 50%. The US president told steel workers: “We are going to be imposing a 25% …

Source: The Guardian - Center-left
Published on May 29, 2025

SVEP1 enables efficient binding of Angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream ...

Lymphatic vessels are closely associated to blood vessels, and malformations of the lymphatic vasculature lead to lymphedema, obesity, or chronic inflammatory diseases (Mäkinen et al. 2021; Petrova and Koh 2018). Next to the well described lymphatic VEGFC…

Source: eLife - Pending
Published on May 29, 2025

This Week’s CGT News: The Next Generation of AAVs

Researchers working on the next generation of AAVs Researchers at Children’s Hospital of Philadelphia (CHOP) have developed novel AAV vectors that significantly improve the precision and efficiency of gene therapy delivery to the brain. In two recent …

Source: The Medicine Maker - Neutral
Published on May 29, 2025

Kashmir University Researchers Create India’s First Gene-Edited Sheep Using CRISPR Technology

The lamb, developed at the university’s Centre for Animal Biotechnology, has an edited myostatin gene that boosts muscle growth. (Photo Source: SKUAST) A group of researchers at Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST- …

Source: Krishi Jagran - Neutral
Published on May 29, 2025

Kashmir University Scientists Pioneer India's First CRISPR-Edited Sheep

SKUAST-Kashmir scientists developed India's first gene-edited sheep using CRISPR-Cas9, targeting the myostatin gene to boost muscle growth. Vice Chancellor Dr. Nazir Ahmad Ganai and the research team highlighted the achievement as a milestone for …

Source: Silicon India - Neutral
Published on May 29, 2025

Climate-resilient crops promise relief for NC farmers

North Carolina growers know all too well how roller-coaster weather can wipe out a season. Last year’s string of flash floods, scorching heat and months of drought left fields parched or waterlogged. Farmers across the state worry that without reliable …

Source: WRAL 5 - North Carolina - Neutral
Published on May 28, 2025

Type I interferon responses contribute to immune protection against mycobacterial infection

Mycobacterium tuberculosis (Mtb) infection results in diverse clinical manifestations, ranging from asymptomatic infection to active tuberculosis (TB), which comprises an enormous spectrum of disease severity 1,2. Although we know that immune responses …

Source: eLife - Pending
Published on May 28, 2025

Scientists develop gene delivery ‘trucks’ that could treat brain diseases

Avery Hunker prepares materials for research at the Allen Institute. (Jenny Burns/Allen Institute) Scores of researchers have produced new tools that can deliver genes and selectively activate them in hundreds of different cell types in the brain and …

Source: Anchorage Daily News - Alaska - Neutral
Published on May 28, 2025

Inside the Discord Community Developing Its Own Hair Loss Drugs

So, you’ve got a receding hairline in 2025. You could visit a dermatologist, sure, or you could try a new crop of websites that will deliver your choice of drugs on demand after a video call with a telehealth physician. There’s Rogaine and products from …

Source: 404 Media - Neutral
Published on May 27, 2025

The New Dark Age

The warlords who sacked Rome did not intend to doom Western Europe to centuries of ignorance. It was not a foreseeable consequence of their actions. The same cannot be said of the sweeping attack on human knowledge and progress that the Trump …

Source: The Atlantic - Neutral
Published on May 28, 2025

After Pashmina Goat, SKUAST Scientists Clone Gene-Edited Sheep in Kashmir

SRINAGAR: In a landmark scientific breakthrough, researchers at the Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST), Kashmir, have successfully produced India’s first gene-edited sheep, without introducing any foreign DNA, …

Source: Kashmir Life - Pending
Published on May 28, 2025

India's first gene-edited sheep developed by Kashmir university researchers. All you need to know

Researchers at a Kashmir-based Agricultural university have produced India's first gene-edited sheep, marking a historic milestone in the field of animal biotechnology. The Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST) has …

Source: Mint - Neutral
Published on May 28, 2025

'Leap Akin To AI Revolution': Kashmir University Researchers Produce India's First Gene-Edited Sheep

Last Updated:May 27, 2025, 23:46 IST The edited sheep contains no foreign DNA, distinguishing it from transgenic organisms and paving the way for regulatory approval under India's evolving biotech policy framework The researchers said the gene-edited …

Source: News18 - Center-right
Published on May 27, 2025

When the worm won’t wait: Battling Fall Armyworm with science, seeds and farmer-led solutions

The destructive Fall armyworm in a farmer’s field (CIMMYT) Farmers in southern Africa face a double tragedy: drought in one season or flooded fields in another. Shredded leaves, twisted tassels, and frizzled maize cobs reflect more than just a failed …

Source: International Maize and Wheat Improvement Center (CIMMYT) - Pending

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Published on May 31, 2025 - 12:00 GMT

ImPact Biotech Presents Interim Analysis from Phase 3 ENLIGHTED Study of Padeliporfin VTP in LG UTUC at ASCO 2025

– Complete response (CR) observed in 73% (27/37) of evaluable patients with low-grade upper tract urothelial cancer (UTUC) who completed the Induction Treatment Phase (ITP) – – Padeliporfin VTP treatment continues to be safe and well-tolerated, …

Distribution channels: Technology ...
Published on May 31, 2025 - 12:00 GMT

Arvinas and Pfizer's Vepdegestrant Significantly Improves Progression-Free Survival for Patients with ESR1-Mutant, ER+/...

Pivotal Phase 3 VERITAC-2 clinical trial results presented at ASCO demonstrate 2.9-month improvement in median progression-free survival when compared to fulvestrant in second line-plus patients with an estrogen receptor 1 mutation Vepdegestrant was …

Distribution channels: Companies, Culture, Society & Lifestyle ...

Published on May 30, 2025 - 14:47 GMT

Fortress Biotech Announces Closing of Sale of Subsidiary Checkpoint Therapeutics

MIAMI, May 30, 2025 (GLOBE NEWSWIRE) -- Fortress Biotech, Inc. (Nasdaq: FBIO) (“Fortress”), an innovative biopharmaceutical company focused on acquiring and advancing assets to enhance long-term value for shareholders through product revenue, equity …

Distribution channels: Companies, Technology ...
Published on May 30, 2025 - 13:14 GMT

PharmAla Biotech Warns Against Fake Products Claiming to be Made by PharmAla

TORONTO, May 30, 2025 (GLOBE NEWSWIRE) -- PharmAla Biotech Holdings Inc. (“PharmAla” or the “Company”) (CSE: MDMA) (OTC: MDXXF), a biotechnology company focused on the research, development, and manufacturing of LaNeo™ MDMA and novel derivatives of MDMA ( …

Distribution channels: Environment, Healthcare & Pharmaceuticals Industry ...

Published on May 30, 2025 - 11:30 GMT

Adaptive Biotechnologies Highlights New Data at 2025 ASCO Annual Meeting and EHA 2025 Congress Demonstrating How ...

SEATTLE, May 30, 2025 (GLOBE NEWSWIRE) -- Adaptive Biotechnologies Corporation (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, …

Distribution channels: Culture, Society & Lifestyle, Healthcare & Pharmaceuticals Industry ...
Published on May 29, 2025 - 22:34 GMT

VERAXA Biotech to Attend Key Industry Conferences to Showcase BiTAC Technology Platform

ZURICH, May 29, 2025 (GLOBE NEWSWIRE) -- VERAXA Biotech AG (“VERAXA”), an emerging leader in designing novel cancer therapies and proposed de-SPAC acquisition target of Voyager Acquisition Corp. (NASDAQ:VACH, “Voyager”), announced today it will be …

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Published on May 29, 2025 - 21:05 GMT

Kane Biotech Announces First Quarter 2025 Financial Results

WINNIPEG, Manitoba, May 29, 2025 (GLOBE NEWSWIRE) -- Kane Biotech Inc. (TSX-V:KNE) (“Kane Biotech”, “Kane” or the “Company”) today announces its first quarter 2025 financial results. First Quarter 2025 Financial Highlights (Comparatives Exclude …

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Published on May 29, 2025 - 14:34 GMT

VERAXA Biotech to Attend Key Industry Conferences to Showcase BiTAC Technology Platform

ZURICH, SWITZERLAND, May 29, 2025 -- VERAXA Biotech AG (“VERAXA”), an emerging leader in designing novel cancer therapies and proposed de-SPAC acquisition target of Voyager Acquisition Corp. (NASDAQ:VACH, “Voyager”), announced today it will be attending …

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Published on May 31, 2025 - 07:00 GMT

PlanChecker AI Launches with the Goal to Rewire the Infrastructure of Real Estate Development

LOS ANGELES, CA, UNITED STATES, May 31, 2025 /⁨EINPresswire.com⁩/ -- Co-founded by veteran real estate developer Matthew Raanan and senior software engineer Justine Raanan, the Los Angeles-based startup PlanCheker AI launches as an innovative …

Distribution channels: Banking, Finance & Investment Industry, Building & Construction Industry ...
Published on May 31, 2025 - 02:00 GMT

Silicon Valley Hair Institute Announces Updated Content on Eyebrow Transplantation

Silicon Valley Hair Institute is excited to announce updated content for eyebrow transplantation. SAN FRANCISCO, CA, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Silicon Valley Hair Institute, the Bay Area leader in hair transplant and …

Distribution channels: Automotive Industry, Beauty & Hair Care ...
Published on May 31, 2025 - 12:00 GMT

Immatics IMA203 PRAME Cell Therapy Data Presented at 2025 ASCO Annual Meeting Continues to Show Strong Anti-tumor ...

Extended Phase 1b trial follow-up on IMA203 PRAME cell therapy in 33 heavily pretreated patients with metastatic melanoma demonstrates favorable tolerability and promising clinical activity with ongoing deep and durable objective responses up to >2.5 …

Distribution channels: Media, Advertising & PR, Technology ...
Published on May 31, 2025 - 12:00 GMT

ImPact Biotech Presents Interim Analysis from Phase 3 ENLIGHTED Study of Padeliporfin VTP in LG UTUC at ASCO 2025

– Complete response (CR) observed in 73% (27/37) of evaluable patients with low-grade upper tract urothelial cancer (UTUC) who completed the Induction Treatment Phase (ITP) – – Padeliporfin VTP treatment continues to be safe and well-tolerated, …

Distribution channels: Technology ...
Published on May 31, 2025 - 12:00 GMT

Harbinger Health Showcases Multi-Cancer Early Detection Performance in High-Risk Populations at ASCO 2025

Reflex blood-based multi-cancer early detection (MCED) test demonstrated clinically meaningful per-cancer Positive Predictive Value (PPV) and early-stage sensitivity for multiple cancers with elevated incidence and mortality in a high-risk population Data …

Distribution channels: Healthcare & Pharmaceuticals Industry, Technology ...
Published on May 30, 2025 - 23:40 GMT

Readers' Favorite Announces a Five-Star Rating for Award-Winning ‘Disrupt with Impact’ by Roger Spitz

Roger Spitz’s Bestselling ‘Disrupt with Impact: Achieve Business Success in an Unpredictable World’ Awarded Five-Star Rating from Readers’ Favorite SAN FRANCISCO, CA, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Following a string of …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on May 30, 2025 - 22:19 GMT

Log-hub and OPTANO: A Unified Approach to Smarter, End-to-End Supply Chain Optimization

Log-hub and OPTANO have partnered to support supply chain professionals with a flexible, end-to-end approach to network design and optimization. SCHINDELLEGI, SWITZERLAND, May 31, 2025 /⁨EINPresswire.com⁩/ -- Log-hub and OPTANO have joined forces …

Distribution channels: Companies, Consumer Goods ...
Published on May 30, 2025 - 22:13 GMT

Présentation du bracelet chrétien Tap2Read : un bracelet innovant pour des inspirations quotidiennes

Présentation du bracelet chrétien Tap2Read : un bracelet innovant pour des inspirations quotidiennes IKEJA, LAGOS, NIGERIA, May 30, 2025 /⁨EINPresswire.com⁩/ -- Dans un monde rempli d’incertitude, de stress, d’anxiété, de dépression et de …

Distribution channels: Agriculture, Farming & Forestry Industry, Business & Economy ...
Published on May 30, 2025 - 22:11 GMT

Route Optimization Cockpit: Smarter Transport Planning through Automation and Insight

Log-hub and KNIME have launched the Route Optimization Cockpit for automated daily route planning and delivering insights through interactive dashboards. SCHINDELLEGI, SWITZERLAND, May 31, 2025 /⁨EINPresswire.com⁩/ -- Log-hub and KNIME have joined …

Distribution channels: Consumer Goods, IT Industry ...
Published on May 30, 2025 - 20:52 GMT

Server5.click Announces Launch of Free Web Hosting Server5.click — A New, Completely Free Web Hosting Service

Server5.click launches free web hosting server5.click — a reliable, no-cost web hosting platform ready for public use after successful beta testing. DUBROVNIK, DUBROVACKO NERETVANSKA, CROATIA, May 30, 2025 /⁨EINPresswire.com⁩/ -- Server5.click is proud to …

Distribution channels: IT Industry, International Organizations ...
Published on May 30, 2025 - 20:46 GMT

Nomadic Advertising Reflects on Two Years Post-Collision Conference, Highlights Continued Client Growth and Innovation

Nomadic Advertising: 2 Years post-Collision, client growth continues. Expanded 15-person team leverages specialized talent & AI for client value. TORONTO, ONTARIO, CANADA, May 30, 2025 /⁨EINPresswire.com⁩/ -- Nomadic Advertising, a full-service …

Distribution channels: Companies, Conferences & Trade Fairs ...
Published on May 30, 2025 - 20:44 GMT

Xtel Communications Joins AppDirect Marketplace to Expand Channel Access to Communications and Cybersecurity Solutions

Leading solution provider to healthcare, education, and government organizations expands distribution MOUNT LAUREL, NJ, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Xtel Communications, a leading provider of next-generation communications …

Distribution channels: Technology ...
Published on May 30, 2025 - 20:16 GMT

Spanglish Movies Partners with Claro to Bring FLOUtv to Puerto Rican Audiences

Spanglish Movies is thrilled to announce a strategic partnership with Claro to deliver FLOUtv's innovative programming to Puerto Rican viewers. MIAMI, FL, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Spanglish Movies, a leading media …

Distribution channels: Banking, Finance & Investment Industry, Companies ...
Published on May 30, 2025 - 20:12 GMT

Trimlight Redefines Outdoor Lighting Safety By Reducing Ladder Accident Risks

Ladder-related accidents are a common risk during outdoor lighting installations. WEST JORDAN, UT, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Ladder-related accidents are a common risk during outdoor lighting installations. Trimlight …

Distribution channels: Building & Construction Industry, Business & Economy ...
Published on May 30, 2025 - 20:07 GMT

ACM CPA Alerts Brampton Business Owners: QuickBooks Desktop 2022 Support Ending May 31, 2025 – Act Now

ACM CPA warns Brampton businesses about QuickBooks 2022 discontinuation and offers expert guidance on upgrades, tax planning, and financial services. BRAMPTON, ONTARIO, CANADA, May 30, 2025 /⁨EINPresswire.com⁩/ -- ACM CPA, a trusted provider of …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on May 30, 2025 - 19:46 GMT

Anne Marie Otáñez Joins Utah Black Chamber Board, Advancing Inclusive Leadership and Community Empowerment

Anne Marie Otáñez joins Utah Black Chamber Board, advancing inclusive leadership, community impact, and support for Black professionals and entrepreneurs. SALT LAKE CITY, UT, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Executive coach, …

Distribution channels: Business & Economy, International Organizations ...
Published on May 31, 2025 - 07:00 GMT

PAIRMiner Launches $150 Cloud Mining Incentive as Institutional Bitcoin Holdings Reach Historic Levels

Amid a surge in institutional Bitcoin investments, PAIRMiner introduces a free cloud mining offer to make crypto access easier for everyday users. Image by PAIRMiner LOS ANGELES, May 31, 2025 (GLOBE NEWSWIRE) -- Cloud mining platform PAIRMiner today …

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Published on May 30, 2025 - 18:30 GMT

Electronic Warfare Market to Grow Sharply USD 35.8 billion by 2035 Amid Rising Defense Budgets and Tech Innovations

Electronic warfare market is expanding as nations invest in advanced tech and defense systems to counter evolving global threats and digital warfare. NEWARK, DE, UNITED STATES, May 31, 2025 /⁨EINPresswire.com⁩/ -- The electronic warfare market is …

Distribution channels: Technology ...
Published on May 30, 2025 - 18:28 GMT

Cosmetic Dentistry Experts Drs. John and Jade Moreau of Unforgettable Smiles Talk How Enhanced Smiles Build Confidence

ALEXANDRIA, LA, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Drs. John and Jade Moreau of Unforgettable Smiles is featured in the latest edition of HelloNation, where he shares valuable insight on the role of cosmetic dentistry in improving both …

Distribution channels: Beauty & Hair Care, Business & Economy ...
Published on May 30, 2025 - 18:26 GMT

LOCAL City Places Launches $CASH$BATES$: Real Cash Rewards for Shopping Local

Consumers simply snap a photo of their receipt and submit. CHANDLER, AZ, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- LOCAL City Places, the nationwide movement helping local merchants stand out, has launched a new kind of loyalty program. Meet $ …

Distribution channels: Business & Economy, Companies ...