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Published on 17:05 GMT

GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes

CRISPR-Cas9 (i.e., Clustered regularly interspaced short palindromic repeats-associated endonuclease 9) mediated gene-editing is widely used to engineer the mammalian genome 1–4. Cas9 cleaves the genome at specific guide RNA (gRNA) target sites generating …

Source: eLife - Label Pending
Published on 17:05 GMT

Kinesin Autoinhibition Requires Elbow Phosphorylation

Kinesin motor proteins, integral to intracellular transport along microtubules, are tightly regulated for precise cargo delivery within cells (Burute and Kapitein, 2019; Christensen and Reck-Peterson, 2022; Hirokawa et al., 2009; Ou and Scholey, 2022). …

Source: eLife - Label Pending
Published on 12:15 GMT

Madras High Court cements scope of protection for non-murine antibodies in setting aside IPO refusal order

In Kymab v Assistant Controller of Patents & Designs, the Madras High Court has clarified the exclusion scope of the production method of non-murine antibodies under Section 3(i) of the Patents Act 1970. The court set aside the Indian Patent Office ( …

Source: Intellectual Asset Management - Label Pending
Published on 12:55 GMT

Physicochemical Property Effects on Immune Modulating Polymeric Nanoparticles: Potential Applications in Spinal Cord ...

Introduction Spinal cord injury (SCI) results in loss of sensation, movement, and autonomic functions of the body below the level of injury.1,2 The time course of SCI can be divided into two phases: the primary injury and prolonged secondary injury.3,4 The …

Source: Dove Medical Press - Neutral
Published on 06:09 GMT

Scientists Crack the Blood-Brain Barrier, Paving Way for New Alzheimer’s Treatments

Researchers at the Icahn School of Medicine at Mount Sinai have developed a groundbreaking system, the blood-brain barrier-crossing conjugate (BCC), which uses γ-secretase-mediated transcytosis to safely deliver large therapeutic molecules into the brain …

Source: SciTechDaily - Neutral
Published on 03:57 GMT

Aldwinckle, Wiesner elected to National Academy of Inventors

For their work on strengthening food crops against pests and diseases, and on hybrid materials for applications including cancer therapeutics, respectively, Cornell professors Herb Aldwinckle and Ulrich Wiesner have been elected fellows of the National …

Source: Cornell Chronicle - New York - Neutral
Published on Dec 10, 2024

How CRISPR patent issues block Indian farmers from accessing biotech benefits

Increasingly, agricultural scientists in Asia and Africa are using the gene-editing tool CRISPR to develop disease-resistant, high-yield crop varieties. Many, especially those in government research laboratories, are underestimating the importance of the …

Source: Nature - Neutral
Published on Dec 10, 2024

Stealth-Engineered Albumin-Coated Nanoparticles for Targeted Therapy: Effective Drug Delivery and Tumor Suppression in ...

Introduction Nanoparticles (NPs) are gaining increasing interest in the medical field due to their intrinsic and extrinsic properties.1–3 Among the various NPs available, synthetic polymers that are both biodegradable and biocompatible hold significant …

Source: Dove Medical Press - Neutral
Published on Dec 10, 2024

Gene mutation likely cause of autism in early childhood: RGCB Study

Thiruvananthapuram: Autism, a developmental disorder that causes functional abnormalities in brain development, is influenced by a combination of genetic and environmental factors, with symptoms appearing in early childhood, according to a study by the …

Source: ET Healthworld - Center-right
Published on Dec 10, 2024

Estrogen Receptor β Alleviates Colitis by Inhibiting Ferroptosis in Intestinal Epithelial Cells

Introduction Ulcerative colitis (UC), one of the principal types of inflammatory bowel disease (IBD), is a chronic and relapsing inflammatory disorder of the gastrointestinal tract.1 UC predominantly affects the mucosal and submucosal layers of the colon …

Source: Dove Medical Press - Neutral
Published on Dec 9, 2024

“Mexico is doing everything possible to protect the USMCA” (Undersecretary of Economy)

9 Mexico is working on security and migration issues to “sit at the table” and negotiate “without obstacles,” Rosendo Gutierrez told a US media outlet. The Mexican government is doing everything possible to protect the North American trade agreement with …

Source: The Yucatan Times - Neutral
Published on Dec 9, 2024

Corn Earworm Building Up More Resistance to Crop Protection Efforts

To minimize damage and reduce the need for insecticide sprays, crops have been genetically engineered to produce bacterial proteins that kill key pests but are not harmful to people or wildlife. However, widespread planting of such transgenic crops has led …

Source: DGR News - Neutral
Published on Dec 9, 2024

Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

The lens is an exemplary model for studying signaling pathways (Cvekl and Zhang, 2017). In mice, the lens placode emerges as thickened epithelia within the lateral head ectoderm at E9.5 (Fig. 1A). It undergoes invagination to form the lens pit at E10.5, …

Source: eLife - Label Pending
Published on Dec 9, 2024

New Seeds, New Opportunities: INTA Revolutionizes Soybean Breeding with Two Innovative Cultivars

Instituto Nacional de Tecnología Agropecuaria introduces INTA Paraná 5100 and INTA Paraná 6301, two new non-transgenic soybean varieties with high protein value and adapted to growers’ needs. In a world context where sustainability and quality are …

Source: Seed World - Label Pending
Published on Dec 9, 2024

Anavex Life Sciences to Report New Long-Term Oral Blarcamesine Phase IIb/III Alzheimer’s Disease Data at J.P. Morgan ...

Topline data from ATTENTION-AD Open-Label-Extension (OLE) 96/144-Week trial J.P. Morgan 2025 Healthcare Conference, taking place January 13–16, 2025, in San Francisco, CA NEW YORK, Dec. 09, 2024 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” …

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Published on Dec 8, 2024

Characterization of Myeloid Cell Hyperactivation Syndrome and...

Date: December 17, 2024 Time: 11:00am PT, 2:00pm ET Super immunodeficient mice such as the NOG-EXL and NSG-SGM3 combine severe immunodeficiency with transgenic expression of human myeloid-stimulatory cytokines. These mouse strains support an improved …

Source: Labroots - California - Neutral
Published on Dec 8, 2024

High-fiber diet may slow progression of precursor conditions to multiple myeloma

December 07, 2024 4 min read Add topic to email alerts Subscribe We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Back to Healio Key takeaways: The diet …

Source: Healio News - Neutral
Published on Dec 7, 2024

A brainstem circuit controls cough-like airway defensive behaviors in mice

Breathing is essential for maintaining homeostasis of O2 and CO2 in mammals and is subject to precise neural control. Various innate defensive reflexes, such as apnea, sneezing, coughing, and expiratory reflexes, are crucial for protecting the airways from …

Source: eLife - Label Pending
Published on Dec 7, 2024

GPR30 in spinal cholecystokinin-positive neurons modulates neuropathic pain via mediating descending facilitation

Neuropathic pain is a common chronic pain condition caused by a lesion or dysfunction of the somatosensory nervous system and affects nearly 7-10% of the population worldwide1–4. Neuropathic pain is characterized by mechanical allodynia, under which …

Source: eLife - Label Pending

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Published on December 11, 2024 - 16:23 GMT

Biotechnology Market | Pioneering Innovations in Healthcare, Agriculture, and Sustainability for a Transformative Future

The Biotechnology Market is experiencing rapid growth, driven by advancements in genetic engineering, biopharmaceuticals, and agricultural biotechnology. AUSTIN, TX, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- The Biotechnology …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on December 11, 2024 - 14:00 GMT

Levostar Biotech Expands into the US Biopharma Market to Support RNA Medicines

Levostar Biotech Expands into the US Biopharma Market to Support RNA Medicines for cell and gene therapies, antibodies, and RNA therapies and vaccines. LEWES, DE, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- Levostar Biotech, an …

Distribution channels: Healthcare & Pharmaceuticals Industry ...

Published on December 11, 2024 - 14:00 GMT

BPC 157 & TB 500: Limitless Biotech Unveils Peptide For Healing & Recovery

Gulf Breeze, FL, Dec. 11, 2024 (GLOBE NEWSWIRE) -- Limitless Biotech, a leader in cutting-edge biotechnology and health solutions, is excited to announce the release of its groundbreaking peptide combination, BPC 157 and TB 500. This dynamic duo is …

Distribution channels: Consumer Goods, Culture, Society & Lifestyle ...
Published on December 11, 2024 - 13:30 GMT

Gain Therapeutics To Present At Biotech Showcase 2025

BETHESDA, Md., Dec. 11, 2024 (GLOBE NEWSWIRE) -- Gain Therapeutics, Inc. (Nasdaq: GANX) (“Gain”, or the “Company”), a clinical-stage biotechnology company leading the discovery and development of the next generation of allosteric small molecule therapies, …

Distribution channels: Culture, Society & Lifestyle, Healthcare & Pharmaceuticals Industry ...

Published on December 10, 2024 - 14:58 GMT

Gene Synthesis Market to Hit USD 9.64 Billion by 2032, Driven by Innovations in Biotechnology and Healthcare

Market growth fueled by advancements in automation, CRISPR technology, and high-throughput sequencing, with a projected CAGR of 17.41% during 2024-2032. AUSTIN, TX, UNITED STATES, December 10, 2024 /⁨EINPresswire.com⁩/ -- The Gene Synthesis Market …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on December 10, 2024 - 18:09 GMT

Two Biotech CEOs Convicted in Securities Fraud Scheme

A federal jury in Maryland convicted two men yesterday for their roles in a scheme to lie to investors in CytoDyn Inc., a publicly traded biotechnology company based in Vancouver, Washington. According to court documents and evidence presented at trial, …

Distribution channels: U.S. Politics
Published on December 10, 2024 - 13:31 GMT

Ori Biotech and Fresenius Kabi Collaborate to Advance Modular, Scalable Manufacturing of Cell and Gene Therapies

LONDON and BAD HOMBURG, Germany, Dec. 10, 2024 (GLOBE NEWSWIRE) -- Ori Biotech Ltd. (Ori), a leader in cell and gene therapy (CGT) manufacturing technology, and Fresenius Kabi, an operating company of Fresenius, today announced a collaboration to integrate …

Distribution channels: Companies, Healthcare & Pharmaceuticals Industry ...
Published on December 11, 2024 - 14:07 GMT

Phenocell and Amarna Therapeutics Awarded Eurostars Grant to Assess a Gene Therapy for Dry AMD using a novel 3-...

Grasse, France and Leiden, the Netherlands – 11 December 2024 – Phenocell SAS (part of Axol Bioscience) a leading provider of stem cell-derived models and services, and Amarna Therapeutics, a biotechnology pioneer in innovative gene therapies, are pleased …

Distribution channels: Healthcare & Pharmaceuticals Industry, Media, Advertising & PR ...

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Published on December 11, 2024 - 19:44 GMT

A.R.T. Digital Holdings Corp. Completes Strategic Acquisition of Kaboomracks to Expand Digital Energy

A.R.T. Digital Holdings acquisition of Kaboomracks to expand hosting, co-location, and energy-efficient solutions for the digital energy. ART Digital Holdings Corp (OTCQX:CGAC) AUSTIN, TX, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- …

Distribution channels: Business & Economy, Energy Industry ...
Published on December 11, 2024 - 19:21 GMT

12th Annual Louisiana IT Symposium Announces Louisiana Technology Leaders of the Year

The Louisiana IT Symposium brings together IT Executives and their teams to network and learn. Technology Leaders of 2024 were awarded. NEW ORLEANS, LA, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- The cream of Louisiana’s IT community …

Distribution channels: Business & Economy, Companies ...
Published on December 11, 2024 - 19:04 GMT

Soutron Global Acquires MINISIS, a Vancouver-based Provider of Archive, Library and Museum Management Software

SAN DIEGO, CA, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- Soutron Global, an internationally recognized provider of information management solutions for corporate libraries and digital archives announces the acquisition of MINISIS, a …

Distribution channels: Companies, IT Industry ...
Published on December 11, 2024 - 18:57 GMT

CognitiveHealth Technologies Introduces Advanced Revenue Cycle Management Tools for Behavioral Health Providers

Cognitive Health IT introduces tailored tools to enhance efficiency and accuracy in revenue cycle management for behavioral health providers. NY, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- Behavioral health providers are poised to …

Distribution channels: Healthcare & Pharmaceuticals Industry, Technology ...
Published on December 11, 2024 - 18:57 GMT

ClearGov Wins Gold in Brandon Hall Group’s Excellence in Technology Awards

ClearGov awarded for advancing learning management technology and empowering local governments MAYNARD, MA, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- ClearGov, the leading provider of budgeting and management solutions for local …

Distribution channels: Business & Economy, Companies ...
Published on December 11, 2024 - 18:55 GMT

Dr. Ozan Ozerk inspires fellow entrepreneurs at FinTech Connect

Dr. Ozan Ozerk, OpenPayd founder, keynoted FinTech Connect on Dec 5, sharing insights on building a fintech ecosystem with industry leaders. ISTANBUL, TURKEY, December 11, 2024 /⁨EINPresswire.com⁩/ -- Dr. Ozan Ozerk, founder of global payment …

Distribution channels: Banking, Finance & Investment Industry, Companies ...
Published on December 11, 2024 - 18:52 GMT

AUVSI Announces Green UAS Certification for Four Drone Platforms

UAS platforms added to Green UAS list maintain proof of NDAA compliance. ARLINGTON, VA, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- The Association for Uncrewed Vehicle Systems International (AUVSI) today announced that it has …

Distribution channels: Aviation & Aerospace Industry, International Organizations ...
Published on December 11, 2024 - 18:41 GMT

Artists Dillon Forte And Andrea De Leon Unveil Revolutionary Tattoo Machine That Combines Art And Innovation

The tattoo machine is handmade with the finest materials and groundbreaking, patent-pending technology. AUSTIN, TX, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- Texas area tattoo artist and entrepreneur Dillon Forte recently partnered …

Distribution channels: Consumer Goods, Culture, Society & Lifestyle ...
Published on December 11, 2024 - 18:40 GMT

Myntex Empowers Mobile Device Security with New eStore

Urging Encryption Adoption in Wake of Chinese Telecom Hack CALGARY, AB, CANADA, December 11, 2024 /⁨EINPresswire.com⁩/ -- Myntex, a leading provider of mobile device security, is taking decisive action to address the growing threat of …

Distribution channels: Banking, Finance & Investment Industry, Law ...
Published on December 11, 2024 - 18:40 GMT

Top International Award for RNT Foundation's Goward

International navigation group recognizes one person every three years ALEXANDRIA, VA, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- The Resilient Navigation and Timing Foundation board of directors is pleased to announce the foundation …

Distribution channels: Aviation & Aerospace Industry, IT Industry ...
Published on December 11, 2024 - 18:22 GMT

FISCAL Technologies and Proservartner Forge Strategic Partnership to Revolutionise Financial Risk Management

READING, UNITED KINGDOM, December 11, 2024 /⁨EINPresswire.com⁩/ -- FISCAL Technologies, a global leader in accounts payable risk management solutions, and Proservartner, a renowned business transformation consultancy, are thrilled to announce a …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on December 11, 2024 - 18:19 GMT

SaferWatch Elevates Executive Protection with 24/7/365 Monitoring and Direct Law Enforcement Connectivity

FORT LAUDERDALE, FL, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- SaferWatch, a leader in advanced safety and security solutions, has unveiled its comprehensive Executive Protection service, designed to provide unmatched security for …

Distribution channels: Banking, Finance & Investment Industry, Companies ...
Published on December 11, 2024 - 18:16 GMT

Case Study: Randamu & Proof of Play Collaborate to Revolutionize Verifiable Randomness for Pirate Nation

BANGKOK, THAILAND, December 11, 2024 /⁨EINPresswire.com⁩/ -- The recent DEVCON Southeast Asia Convention in Bangkok, Thailand, sponsored by the Ethereum Foundation, showcased a bevy of new technologies, including cutting-edge innovations in onchain …

Distribution channels: Amusement, Gaming & Casino, Business & Economy ...
Published on December 11, 2024 - 18:12 GMT

Messageware Launches Z-Day Guard V2.0: Advanced Multi-Server Cyberattack Monitoring

Announcing Z-Day Guard V2 with multi-server dashboards and health reports, simplifying detection and response to zero-day vulnerabilities and cyberattacks. TORONTO, CANADA, December 11, 2024 /⁨EINPresswire.com⁩/ -- Messageware Incorporated, a …

Distribution channels: Banking, Finance & Investment Industry, Healthcare & Pharmaceuticals Industry ...
Published on December 11, 2024 - 18:07 GMT

Fusion Flow Launches AI Booster to Maximize ROI for Data-Driven Enterprises

DE, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- Fusion Flow, a trailblazer in AI-driven innovation within the ERP ecosystem, has announced the launch of its groundbreaking AI Booster. Designed to maximize return on investment (ROI), …

Distribution channels: Business & Economy, Companies ...
Published on December 11, 2024 - 17:54 GMT

AV8 Realty Expands to Spruce Creek Fly-In (7FL6), Welcoming Managing Broker Dave Scheidl

AV8 Realty: The Pioneering Online Platform Transforming Aviation Real Estate PORT ORANGE, FL, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- Florida, 12/11/24– AV8 Realty, the premier aviation real estate brokerage, is thrilled …

Distribution channels: Aviation & Aerospace Industry, IT Industry ...
Published on December 11, 2024 - 17:53 GMT

Top Internal Developer Platforms 2025

Bunnyshell has been recognized as the top platform for managing Kubernetes and offering an internal developer platform for platform engineering. SAN FRANCISCO, CA, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- Bunnyshell Named Top …

Distribution channels: Companies, IT Industry ...
Published on December 11, 2024 - 17:47 GMT

Peptides As the "Sword": Creative Biolabs Changes Its Target to SARS-CoV-2 Drug Development

Creative Biolabs has recently upgraded its antiviral peptide services so as to aid in antiviral drug development. NY, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- In addition to the core activity of developing a SARS-CoV-2 diagnostic …

Distribution channels: Science, Technology ...
Published on December 11, 2024 - 17:42 GMT

Instant Innovation: Prototek Launches AI-Powered CNC Instant Quote Platform

CONTOOCOOK, NH, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- The leader in custom manufacturing solutions, Prototek, is adding to their cutting-edge Instant Quoting platform, this time for CNC projects. Launching on December 11, the …

Distribution channels: Automotive Industry, Aviation & Aerospace Industry ...
Published on December 11, 2024 - 17:29 GMT

Meritus USA Partners with Creatio to Revolutionize CRM and Business Automation with AI

The partnership brings no-code CRM and AI-driven solutions to empower businesses with unparalleled automation freedom and operational efficiency. BEDMINSTER, NJ, UNITED STATES, December 11, 2024 /⁨EINPresswire.com⁩/ -- Bedminster, NJ, USA — …

Distribution channels: Banking, Finance & Investment Industry, Companies ...